| Read Time: < 1 minute

2013 — In 2013, the FDA was still investigating the link between incretin mimetics and pancreatic disease.  They released a drug safety communication reporting the possibility of incretin mimetics increasing the risk of pancreatitis as well as causing pre-cancerous changes in the pancreas.  They also cited a study, which was unpublished at the time, that found how the use of exenatide or sitagliptin can double the risk of developing acute pancreatitis.

A 2013 study in the medical journal Diabetes found that patients using incretin mimetics had a higher rate of pancreatitis and pancreatic cancer than patients using other diabetes medications.

References:  Center for Drug Evaluation and Research. “FDA Investigating Reports of Possible Increased Risk of Pancreatitis..” U.S. Food and Drug Administration, FDA, www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-investigating-reports-possible-increased-risk-pancreatitis-and-pre. Butler, Alexandra E., et al. “Marked Expansion of Exocrine and Endocrine Pancreas With Incretin Therapy in Humans With Increased Exocrine Pancreas Dysplasia and the Potential for Glucagon-Producing Neuroendocrine Tumors.” Diabetes, American Diabetes Association, 1 July 2013, diabetes.diabetesjournals.org/content/62/7/2595.short.

Author Photo

Gayle Gerling Pettinga

Born and raised in Evansville, Gayle is a respected, experienced lawyer and a valued community leader. She graduated near the top of her class at Indiana University’s prestigious Maurer School of Law. She’s practiced law with one of the largest firms in Indianapolis as well as one of the largest pharmaceutical companies in the world. And that means she knows how big law firms and big companies think and how they operate – and she will put that knowledge to work for you.

Gayle has received numerous awards and honors including Martindale-Hubbell — Peer Review Rated: AV®, American Institute of Personal Injury Attorneys 10 Best Attorneys in Indiana for Exceptional and Outstanding Client Service, and YWCA Evansville 100 Years, 100 Women Honoree, 2011.

Rate this Post

1 Star2 Stars3 Stars4 Stars5 Stars