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GlaxoKlineSmith Ranitidine Patent Expires

1997 — In 1997, GlaxoKlineSmith’s U.S. patent for ranitidine expired.  Competitors were now able to create generic alternatives. Reference:  “Timeline: Popular Heartburn Medicine Zantac Pulled off Store Shelves.” Reuters, Thomson Reuters, 21 Oct. 2019, www.reuters.com/article/us-health-fda-heartburn-timeline/timeline-popular-heartburn-medicine-zantac-pulled-off-store-shelves-idUSKBN1X014E.

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Zantac Experiences Exponential Growth

1988 — In 1988, Zantac became the world’s best selling drug and one of the first drugs to ever top $1 billion in annual sales. Reference:  “Timeline: Popular Heartburn Medicine Zantac Pulled off Store Shelves.” Reuters, Thomson Reuters, 21 Oct. 2019, www.reuters.com/article/us-health-fda-heartburn-timeline/timeline-popular-heartburn-medicine-zantac-pulled-off-store-shelves-idUSKBN1X014E.

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Zantac Approved by FDA

1983 — Zantac was first approved by the FDA and sold in the U.S. in 1983. Reference:  “Timeline: Popular Heartburn Medicine Zantac Pulled off Store Shelves.” Reuters, Thomson Reuters, 21 Oct. 2019, www.reuters.com/article/us-health-fda-heartburn-timeline/timeline-popular-heartburn-medicine-zantac-pulled-off-store-shelves-idUSKBN1X014E.

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